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작성자 Constance Cowpe…
댓글 0건 조회 23회 작성일 25-02-21 01:13

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RelocaTE2 recognized 648 insertion sites while the genome comparison revealed that 93% of insertions were true positives (Fig. 3A). TEMP identified 362 insertions, of which 50% (183/362) overlapped with RelocaTE2 (Fig. 3A). The specificity of TEMP was estimated to be 86%, slightly lower than RelocaTE2 (93%) (Fig. 3A). However, TEMP was found to be less delicate than RelocaTE2 in the rice genome, only calling 362 websites as compared to 648 by RelocaTE2 (38% vs. We evaluated TE identifying instruments in the HuRef genome and benchmark the sensitivity and specificity of these instruments utilizing 574 experimental verified Alu insertions in HuRef genome and genomic comparison between HuRef genome and GRCh36. In comparison to other instruments tested, RelocaTE2 achieves the best stability between sensitivity and specificity. The prolonged runtime limits the feasibility of making use of these tools when looking out 1000's of TEs in a whole bunch or 1000's of individuals. The tool is presented as a useful useful resource for analyzing inhabitants dynamics of TEs in genomic resequencing knowledge. These instruments determine discordant pairs of sequence reads based mostly on the chromosomal position of read alignments to point genomic inversions, insertions, deletions or other complex rearrangements (Campbell et al., 2008; Korbel et al., 2007). Software for TE mapping scrutinize genomic loci with discordant learn pairs to see if identified TE sequences are may be implicated close to the rearrangement site

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